TRIBE editing reveals specific mRNA targets of eIF4E-BP in Drosophila and in mammals

4E-BP (eIF4E-BP) represses translation initiation by binding to the 5′ cap–binding protein eIF4E and inhibiting its activity. Although 4E-BP has been shown to be important in growth control, stress response, cancer, neuronal activity, and mammalian circadian rhythms, it is not understood how it pref...

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Detalles Bibliográficos
Autores principales: Jin, Hua, Xu, Weijin, Rahman, Reazur, Na, Daxiang, Fieldsend, Allegra, Song, Wei, Liu, Shaobo, Li, Chong, Rosbash, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423359/
https://www.ncbi.nlm.nih.gov/pubmed/32851185
http://dx.doi.org/10.1126/sciadv.abb8771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423359/
https://www.ncbi.nlm.nih.gov/pubmed/32851185
http://dx.doi.org/10.1126/sciadv.abb8771

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