Fluoroalkylation promotes cytosolic peptide delivery

Cytosolic delivery of peptides remains a challenging task owing to their susceptibility to enzymatic degradation and the existence of multiple intracellular barriers. Here, we report a new strategy to address these issues by decoration of a fluorous tag on the terminal of cargo peptides. The fluorou...

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Detalles Bibliográficos
Autores principales: Rong, Guangyu, Wang, Changping, Chen, Lijie, Yan, Yang, Cheng, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423368/
https://www.ncbi.nlm.nih.gov/pubmed/32851155
http://dx.doi.org/10.1126/sciadv.aaz1774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423368/
https://www.ncbi.nlm.nih.gov/pubmed/32851155
http://dx.doi.org/10.1126/sciadv.aaz1774

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