A high-content image-based drug screen of clinical compounds against cell transmission of adenovirus

Human adenoviruses (HAdVs) are fatal to immuno-suppressed individuals, but no effective anti-HAdV therapy is available. Here, we present a novel image-based high-throughput screening (HTS) platform, which scores the full viral replication cycle from virus entry to dissemination of progeny and second...

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Detalles Bibliográficos
Autores principales: Georgi, Fanny, Kuttler, Fabien, Murer, Luca, Andriasyan, Vardan, Witte, Robert, Yakimovich, Artur, Turcatti, Gerardo, Greber, Urs F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423605/
https://www.ncbi.nlm.nih.gov/pubmed/32788590
http://dx.doi.org/10.1038/s41597-020-00604-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423605/
https://www.ncbi.nlm.nih.gov/pubmed/32788590
http://dx.doi.org/10.1038/s41597-020-00604-0

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