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SHP-2-Mediated Upregulation of ZEB1 Is Important for PDGF-B-Induced Cell Proliferation and Metastatic Phenotype in Triple Negative Breast Cancer

Background: Triple negative breast cancer (TNBC), a fatal malignant tumor, is characterized by a lack of estrogen and progesterone hormone receptors and overexpression of HER2. Due to its characteristics, there are no effective targeted therapies for TNBC. Therefore, it is critical to identify the c...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Yuan, Chenwei, Peng, Jing, Zhou, Liheng, Jiang, Yiwei, Lin, Yanping, Yin, Wenjin, Xu, Shuguang, Ma, Jun, Lu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423842/
https://www.ncbi.nlm.nih.gov/pubmed/32850368
http://dx.doi.org/10.3389/fonc.2020.01230