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Pathway-specific model estimation for improved pathway annotation by network crosstalk

Pathway enrichment analysis is the most common approach for understanding which biological processes are affected by altered gene activities under specific conditions. However, it has been challenging to find a method that efficiently avoids false positives while keeping a high sensitivity. We here...

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Detalles Bibliográficos
Autores principales: Castresana-Aguirre, Miguel, Sonnhammer, Erik L. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423893/
https://www.ncbi.nlm.nih.gov/pubmed/32788619
http://dx.doi.org/10.1038/s41598-020-70239-z