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Evaluation of cytotoxic T lymphocyte-mediated anticancer response against tumor interstitium-simulating physical barriers

Tumor antigen-specific cytotoxic T lymphocyte (CTL) is a promising agent for cancer therapy. Most solid tumors are characterized by increased interstitial fluid pressure (IFP) and dense collagen capsule, which form physical barriers to impede cancer treatment. However, it remains unclear how CTL-med...

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Detalles Bibliográficos
Autores principales: Chen, Shu-Ching, Wu, Po-Cheng, Wang, Chiao-Yi, Kuo, Po-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423901/
https://www.ncbi.nlm.nih.gov/pubmed/32788651
http://dx.doi.org/10.1038/s41598-020-70694-8