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Inhibition of Wnt signaling pathway suppresses radiation-induced dermal fibrosis

Progressive fibrosis of the dermal tissues is a challenging complication of radiotherapy whose underlying mechanism is not fully understood, and there are few available treatments. The canonical Wnt/β-catenin signaling pathway plays an important role in fibrosis as well as in the epithelial-to-mesen...

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Detalles Bibliográficos
Autores principales: Lee, Dong Won, Lee, Won Jai, Cho, Jaeho, Yun, Chae-Ok, Roh, Hyun, Chang, Hsien Pin, Roh, Tai Suk, Lee, Ju Hee, Lew, Dae Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423922/
https://www.ncbi.nlm.nih.gov/pubmed/32788612
http://dx.doi.org/10.1038/s41598-020-70243-3