Chemical p38 MAP kinase inhibition constrains tissue inflammation and improves antibiotic activity in Mycobacterium tuberculosis-infected mice

Host-modulating therapies have become an important focus in the development of novel concepts for improved management of tuberculosis (TB). Previous in vitro studies revealed that the p38 MAP kinase signaling pathway coordinates several inflammatory and stress responses in Mycobacterium tuberculosis...

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Detalles Bibliográficos
Autores principales: Hölscher, Christoph, Gräb, Jessica, Hölscher, Alexandra, Müller, Annie Linnea, Schäfer, Stephan C., Rybniker, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423948/
https://www.ncbi.nlm.nih.gov/pubmed/32788581
http://dx.doi.org/10.1038/s41598-020-70184-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423948/
https://www.ncbi.nlm.nih.gov/pubmed/32788581
http://dx.doi.org/10.1038/s41598-020-70184-x

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