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Metabolites profiling and pharmacokinetics of troxipide and its pharmacodynamics in rats with gastric ulcer

Troxipide is widely used to treat gastric ulcer (GU) in the clinic. However, a lack of systematic metabolic, pharmacokinetic and pharmacological studies limits its clinical use. This study aimed to firstly explore the metabolic, pharmacokinetic and pharmacological mechanisms of troxipide in rats wit...

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Detalles Bibliográficos
Autores principales: Guo, Hongbin, Chen, Baohua, Yan, Zihan, Gao, Jian, Tang, Jiamei, Zhou, Chengyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423950/
https://www.ncbi.nlm.nih.gov/pubmed/32788674
http://dx.doi.org/10.1038/s41598-020-70312-7