Cargando…

The control of acidity in tumor cells: a biophysical model

Acidosis of the tumor microenvironment leads to cancer invasion, progression and resistance to therapies. We present a biophysical model that describes how tumor cells regulate intracellular and extracellular acidity while they grow in a microenvironment characterized by increasing acidity and hypox...

Descripción completa

Detalles Bibliográficos
Autores principales: Piasentin, Nicola, Milotti, Edoardo, Chignola, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423962/
https://www.ncbi.nlm.nih.gov/pubmed/32788634
http://dx.doi.org/10.1038/s41598-020-70396-1