Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy

Familial amyloid polyneuropathy (FAP) is a neurodegenerative disorder whose major hallmark is the deposition of mutated transthyretin (TTR) in the form of amyloid fibrils in the peripheral nervous system (PNS). The exposure of PNS axons to extracellular TTR deposits leads to an axonopathy that culmi...

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Detalles Bibliográficos
Autores principales: I. Oliveira da Silva, Marina, Lopes, Carla S., Liz, Márcia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423984/
https://www.ncbi.nlm.nih.gov/pubmed/32788615
http://dx.doi.org/10.1038/s41598-020-70377-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423984/
https://www.ncbi.nlm.nih.gov/pubmed/32788615
http://dx.doi.org/10.1038/s41598-020-70377-4

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