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Reduced axonal caliber and structural changes in a rat model of Fragile X syndrome with a deletion of a K-Homology domain of Fmr1

Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene. Neuroanatomical alterations have been reported in both male and female individuals with FXS, yet the morphological underpinnings of these alterations have not been elucidated. In the current study...

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Detalles Bibliográficos
Autores principales: Golden, Carla E. M., Yee, Yohan, Wang, Victoria X., Harony-Nicolas, Hala, Hof, Patrick R., Lerch, Jason P., Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423986/
https://www.ncbi.nlm.nih.gov/pubmed/32788572
http://dx.doi.org/10.1038/s41398-020-00943-x