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Reduced axonal caliber and structural changes in a rat model of Fragile X syndrome with a deletion of a K-Homology domain of Fmr1
Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene. Neuroanatomical alterations have been reported in both male and female individuals with FXS, yet the morphological underpinnings of these alterations have not been elucidated. In the current study...
Autores principales: | Golden, Carla E. M., Yee, Yohan, Wang, Victoria X., Harony-Nicolas, Hala, Hof, Patrick R., Lerch, Jason P., Buxbaum, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423986/ https://www.ncbi.nlm.nih.gov/pubmed/32788572 http://dx.doi.org/10.1038/s41398-020-00943-x |
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