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Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

Quantifying the inducible HIV reservoir provides an estimate of the frequency of quiescent HIV-infected cells in humans as well as in animal models, and can help ascertain the efficacy of latency reversing agents (LRAs). The quantitative viral outgrowth assay (QVOA) is used to measure inducible, rep...

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Detalles Bibliográficos
Autores principales: Stuelke, Erin L., James, Katherine S., Kirchherr, Jennifer L., Allard, Brigitte, Baker, Caroline, Kuruc, Joann D., Gay, Cindy L., Margolis, David M., Archin, Nancie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423995/
https://www.ncbi.nlm.nih.gov/pubmed/32849659
http://dx.doi.org/10.3389/fimmu.2020.01971