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Self-microemulsifying drug delivery system (SMEDDS) of curcumin attenuates depression in olfactory bulbectomized rats

BACKGROUND: Current therapies for depression remain limited and plagued by various side effects. Problems associated with curcumin administration include poor aqueous solubility and bioavailability issues. Hence to overcome these, curcumin self micro emulsifying drug delivery system (SMEDDS) which w...

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Detalles Bibliográficos
Autores principales: Aswar, Manoj, Bhalekar, Mangesh, Trimukhe, Akshata, Aswar, Urmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424201/
https://www.ncbi.nlm.nih.gov/pubmed/32817886
http://dx.doi.org/10.1016/j.heliyon.2020.e04482