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Self-microemulsifying drug delivery system (SMEDDS) of curcumin attenuates depression in olfactory bulbectomized rats
BACKGROUND: Current therapies for depression remain limited and plagued by various side effects. Problems associated with curcumin administration include poor aqueous solubility and bioavailability issues. Hence to overcome these, curcumin self micro emulsifying drug delivery system (SMEDDS) which w...
Autores principales: | Aswar, Manoj, Bhalekar, Mangesh, Trimukhe, Akshata, Aswar, Urmila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424201/ https://www.ncbi.nlm.nih.gov/pubmed/32817886 http://dx.doi.org/10.1016/j.heliyon.2020.e04482 |
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