Cargando…

ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum

Thorax fusion occurs in the midline of the Drosophila pupal notum and involves epithelial cell delamination requiring apoptotic signaling. By genetic screening, we found that NADPH oxidases (Nox and Duox) associated with superoxide anion (O˙(-)(2)) are responsible for caspase-3 activation and delami...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujisawa, Yuya, Shinoda, Natsuki, Chihara, Takahiro, Miura, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424206/
https://www.ncbi.nlm.nih.gov/pubmed/32791328
http://dx.doi.org/10.1016/j.isci.2020.101413