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ROS Regulate Caspase-Dependent Cell Delamination without Apoptosis in the Drosophila Pupal Notum
Thorax fusion occurs in the midline of the Drosophila pupal notum and involves epithelial cell delamination requiring apoptotic signaling. By genetic screening, we found that NADPH oxidases (Nox and Duox) associated with superoxide anion (O˙(-)(2)) are responsible for caspase-3 activation and delami...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424206/ https://www.ncbi.nlm.nih.gov/pubmed/32791328 http://dx.doi.org/10.1016/j.isci.2020.101413 |