Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism

Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant growth of astrocytes. We utilized conditioned media (CM) of...

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Detalles Bibliográficos
Autores principales: Zeng, Ailiang, Wei, Zhiyun, Rabinovsky, Rosalia, Jun, Hyun Jung, El Fatimy, Rachid, Deforzh, Evgeny, Arora, Ramil, Yao, Yizheng, Yao, Shun, Yan, Wei, Uhlmann, Erik J., Charest, Alain, You, Yongping, Krichevsky, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424213/
https://www.ncbi.nlm.nih.gov/pubmed/32795915
http://dx.doi.org/10.1016/j.isci.2020.101420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424213/
https://www.ncbi.nlm.nih.gov/pubmed/32795915
http://dx.doi.org/10.1016/j.isci.2020.101420

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