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Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism
Glioblastoma (GBM) may arise from astrocytes through a multistep process involving a progressive accumulation of mutations. We explored whether GBM-derived extracellular vesicles (EVs) may facilitate neoplastic transformation and malignant growth of astrocytes. We utilized conditioned media (CM) of...
Autores principales: | Zeng, Ailiang, Wei, Zhiyun, Rabinovsky, Rosalia, Jun, Hyun Jung, El Fatimy, Rachid, Deforzh, Evgeny, Arora, Ramil, Yao, Yizheng, Yao, Shun, Yan, Wei, Uhlmann, Erik J., Charest, Alain, You, Yongping, Krichevsky, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424213/ https://www.ncbi.nlm.nih.gov/pubmed/32795915 http://dx.doi.org/10.1016/j.isci.2020.101420 |
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