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Identification and functional characterization of NAD(P)(+)‐dependent meso‐diaminopimelate dehydrogenase from Numidum massiliense

meso‐Diaminopimelate dehydrogenase (meso‐DAPDH) catalyzes the reversible NADP(+)‐dependent oxidative deamination of meso‐2,6‐diaminopimelate (meso‐DAP) to produce l‐2‐amino‐6‐oxopimelate. Moreover, d‐amino acid dehydrogenase (d‐AADHs) derived from protein‐engineered meso‐DAPDH is useful for one‐step...

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Detalles Bibliográficos
Autores principales: Akita, Hironaga, Nakamichi, Yusuke, Morita, Tomotake, Matsushika, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424261/
https://www.ncbi.nlm.nih.gov/pubmed/32485072
http://dx.doi.org/10.1002/mbo3.1059