Cargando…

Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

BACKGROUND: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe of adrenal cortisol secretion. OBJECTIVE: This...

Descripción completa

Detalles Bibliográficos
Autores principales: Roelfsema, Ferdinand, Liu, Peter Y, Yang, Rebecca, Takahashi, Paul, Veldhuis, Johannes D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424344/
https://www.ncbi.nlm.nih.gov/pubmed/32520721
http://dx.doi.org/10.1530/EC-20-0211