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Dually Reactive Long Recombinant Linkers for Bioconjugations as an Alternative to PEG

[Image: see text] Covalent cross-linking of biomolecules can be useful in pursuit of tissue targeting or dual targeting of two receptors on cell surfaces for avidity effects. Long linkers (>10 kDa) can be advantageous for such purposes, and poly(ethylene glycol) (PEG) linkers are most commonly us...

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Detalles Bibliográficos
Autores principales: Kjeldsen, Thomas, Hogendorf, Wouter F. J., Tornøe, Christian W., Anderson, Jonathan, Hubalek, Frantisek, Stidsen, Carsten E., Sorensen, Jan L., Hoeg-Jensen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424725/
https://www.ncbi.nlm.nih.gov/pubmed/32803078
http://dx.doi.org/10.1021/acsomega.0c02712