Effect of salbutamol on neuromuscular junction function and structure in a mouse model of DOK7 congenital myasthenia

Congenital myasthenic syndromes (CMS) are characterized by fatigable muscle weakness resulting from impaired neuromuscular transmission. β2-adrenergic agonists are an effective treatment for DOK7-CMS. DOK7 is a component within the AGRN-LRP4-MUSK-DOK7 signalling pathway that is key for the formation...

Descripción completa

Detalles Bibliográficos
Autores principales: Webster, Richard G, Vanhaesebrouck, An E, Maxwell, Susan E, Cossins, Judith A, Liu, Weiwei, Ueta, Ryo, Yamanashi, Yuji, Beeson, David M W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424765/
https://www.ncbi.nlm.nih.gov/pubmed/32543656
http://dx.doi.org/10.1093/hmg/ddaa116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424765/
https://www.ncbi.nlm.nih.gov/pubmed/32543656
http://dx.doi.org/10.1093/hmg/ddaa116

Ejemplares similares