The alpha-glucosidase inhibitor miglitol increases hepatic CYP7A1 activity in association with altered short-chain fatty acid production in the gut of obese diabetic mice

PURPOSE: Bile acids (BAs) have been shown to contribute to glucose and energy homeostasis. We have recently reported that miglitol, an alpha-glucosidase inhibitor, increases fecal BA excretion and ameliorate insulin resistance and obesity in mice. The aim of this study was to clarify the mechanisms...

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Detalles Bibliográficos
Autores principales: Hamada, Yoji, Goto, Moritaka, Nishimura, Go, Nagasaki, Hiroshi, Seino, Yusuke, Kamiya, Hideki, Nakamura, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424806/
https://www.ncbi.nlm.nih.gov/pubmed/32812937
http://dx.doi.org/10.1016/j.metop.2020.100024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424806/
https://www.ncbi.nlm.nih.gov/pubmed/32812937
http://dx.doi.org/10.1016/j.metop.2020.100024

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