Development of a highly sensitive method for detection of FLT3D835Y

BACKGROUND: Acute myeloid leukemia (AML) is a malignant hematological neoplasm of myeloid progenitor cells. Mutations of FLT3 in its tyrosine kinase domain (FLT3-TKD) are found in ~ 8% of patients with AML, with D835Y as the most common substitution. This mutation activates survival signals that dri...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yao, Sun, Honghua, Zhang, Dengyang, Zhao, Yuming, Shi, Mingxia, Yang, Ming, Xing, Shu, Fu, Xueqi, Bin, Ting, Lu, Bo, Wu, Shunjie, Xu, Xiaojun, Xu, Xuesong, Chen, Yun, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424998/
https://www.ncbi.nlm.nih.gov/pubmed/32817792
http://dx.doi.org/10.1186/s40364-020-00210-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424998/
https://www.ncbi.nlm.nih.gov/pubmed/32817792
http://dx.doi.org/10.1186/s40364-020-00210-7

Ejemplares similares