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Curcumin Conjugates of Non‐steroidal Anti‐Inflammatory Drugs: Synthesis, Structures, Anti‐proliferative Assays, Computational Docking, and Inflammatory Response

In an effort to combine the anti‐proliferative effect of CUR‐BF(2) and CUR compounds with anti‐inflammatory benefits of non‐steroidal anti‐inflammatory drugs (NSAIDs), a library of the bis‐ and mono‐NSAID/CUR‐BF(2) and NSAID/CUR conjugates were synthesized by coupling flufenamic acid, flurbiprofen,...

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Detalles Bibliográficos
Autores principales: Laali, Kenneth K., Zwarycz, Angela T., Beck, Nicholas, Borosky, Gabriela L., Nukaya, Manabu, Kennedy, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425154/
https://www.ncbi.nlm.nih.gov/pubmed/32802728
http://dx.doi.org/10.1002/open.202000173