circAFF1 Aggravates Vascular Endothelial Cell Dysfunction Mediated by miR-516b/SAV1/YAP1 Axis

Pathological vascular endothelial damage caused by hypoxia is the basis of many vascular-related diseases. However, the role of circular RNA in hypoxic vascular injury is still poorly understood. Here, we found that hypoxia induced AFF1 circular RNA (circAFF1) can activate the SAV1/YAP1 and lead to...

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Detalles Bibliográficos
Autores principales: Wang, Hong-guang, Yan, Hua, Wang, Chen, Li, Mi-mi, Lv, Xin-ze, Wu, Hai-dong, Fang, Zhan-hai, Mo, Dong-li, Zhang, Zhi-yuan, Liang, Bin, Lai, Ke-guan, Bao, Jing-yu, Yang, Xue-jia, Zhao, Hong-juan, Chen, Shuang, Fan, Yi-mu, Tong, Xiao-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425207/
https://www.ncbi.nlm.nih.gov/pubmed/32848851
http://dx.doi.org/10.3389/fphys.2020.00899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425207/
https://www.ncbi.nlm.nih.gov/pubmed/32848851
http://dx.doi.org/10.3389/fphys.2020.00899

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