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MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes

Homologous apolipoproteins of MICOS complex, MIC26 and MIC27, show an antagonistic regulation of their protein levels, making it difficult to deduce their individual functions using a single gene deletion. We obtained single and double knockout (DKO) human cells of MIC26 and MIC27 and found that DKO...

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Detalles Bibliográficos
Autores principales: Anand, Ruchika, Kondadi, Arun Kumar, Meisterknecht, Jana, Golombek, Mathias, Nortmann, Oliver, Riedel, Julia, Peifer-Weiß, Leon, Brocke-Ahmadinejad, Nahal, Schlütermann, David, Stork, Björn, Eichmann, Thomas O, Wittig, Ilka, Reichert, Andreas S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425215/
https://www.ncbi.nlm.nih.gov/pubmed/32788226
http://dx.doi.org/10.26508/lsa.202000711