Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU

The mitochondrial calcium uniporter (MCU) is a calcium-activated calcium channel critical for signaling and bioenergetics. MCU, the pore-forming subunit of the uniporter, contains two transmembrane domains and is found in all major eukaryotic taxa. In amoeba and fungi, MCU homologs are sufficient to...

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Detalles Bibliográficos
Autores principales: MacEwen, Melissa JS, Markhard, Andrew L, Bozbeyoglu, Mert, Bradford, Forrest, Goldberger, Olga, Mootha, Vamsi K, Sancak, Yasemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425227/
https://www.ncbi.nlm.nih.gov/pubmed/32769116
http://dx.doi.org/10.26508/lsa.202000718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425227/
https://www.ncbi.nlm.nih.gov/pubmed/32769116
http://dx.doi.org/10.26508/lsa.202000718

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