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Yangxin granules alleviate doxorubicin-induced cardiotoxicity by suppressing oxidative stress and apoptosis mediated by AKT/GSK3β/β-catenin signaling

BACKGROUND: Yangxin granules (YXC), a Chinese herbal medicine, have been confirmed to have clinical benefits in the treatment of heart failure. This study examined the effects and molecular mechanisms of YXC in the treatment of doxorubicin-induced cardiotoxicity in vitro. METHODS: H9c2 cardiomyocyte...

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Detalles Bibliográficos
Autores principales: Ren, Dezhi, Li, Fang, Cao, Qingwen, Gao, An, Ai, Yingna, Zhang, Junru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425278/
https://www.ncbi.nlm.nih.gov/pubmed/32780664
http://dx.doi.org/10.1177/0300060520945161