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Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations

Mitochondrial dysfunction is a common pathological hallmark in various inflammatory and degenerative diseases of the central nervous system, including multiple sclerosis (MS). We previously showed that oxidative stress alters axonal mitochondria, limiting their transport and inducing conformational...

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Detalles Bibliográficos
Autores principales: Malla, Bimala, Cotten, Samuel, Ulshoefer, Rebecca, Paul, Friedemann, Hauser, Anja E., Niesner, Raluca, Bros, Helena, Infante-Duarte, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425321/
https://www.ncbi.nlm.nih.gov/pubmed/32850106
http://dx.doi.org/10.1177/2040622320944773