Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer’s disease models

Clinical and neuropathological studies have shown that tau pathology better correlates with the severity of dementia than amyloid plaque burden, making tau an attractive target for the cure of Alzheimer’s disease. We have explored whether passive immunization with the 12A12 monoclonal antibody (26–3...

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Detalles Bibliográficos
Autores principales: Corsetti, Veronica, Borreca, Antonella, Latina, Valentina, Giacovazzo, Giacomo, Pignataro, Annabella, Krashia, Paraskevi, Natale, Francesca, Cocco, Sara, Rinaudo, Marco, Malerba, Francesca, Florio, Rita, Ciarapica, Roberta, Coccurello, Roberto, D’Amelio, Marcello, Ammassari-Teule, Martine, Grassi, Claudio, Calissano, Pietro, Amadoro, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425324/
https://www.ncbi.nlm.nih.gov/pubmed/32954296
http://dx.doi.org/10.1093/braincomms/fcaa039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425324/
https://www.ncbi.nlm.nih.gov/pubmed/32954296
http://dx.doi.org/10.1093/braincomms/fcaa039

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