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Activation of both transforming growth factor-β and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia

Various ligands and receptors of the transforming growth factor-β superfamily have been found upregulated following traumatic brain injury; however, the role of this signalling system in brain injury pathophysiology is not fully characterized. To address this, we utilized an acute stab wound brain i...

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Detalles Bibliográficos
Autores principales: Divolis, Georgios, Stavropoulos, Athanasios, Manioudaki, Maria, Apostolidou, Anastasia, Doulou, Athanasia, Gavriil, Ariana, Dafnis, Ioannis, Chroni, Angeliki, Mummery, Christine, Xilouri, Maria, Sideras, Paschalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425383/
https://www.ncbi.nlm.nih.gov/pubmed/32954268
http://dx.doi.org/10.1093/braincomms/fcz028