Lysine-specific histone demethylase 1B (LSD2/KDM1B) represses p53 expression to promote proliferation and inhibit apoptosis in colorectal cancer through LSD2-mediated H3K4me2 demethylation

Epigenetic alterations have been reported to play critical roles in the development of colorectal cancer (CRC). However, the biological function of the lysine-specific histone demethylase 1B (LSD2/KDM1B) in CRC is not well understood. Therefore, we investigated the characteristics of LSD2 in CRC. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Shaoxin, Wang, Jinsi, Zeng, Wei, Cheng, Xuefei, Liu, Lihang, Li, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425427/
https://www.ncbi.nlm.nih.gov/pubmed/32726297
http://dx.doi.org/10.18632/aging.103558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425427/
https://www.ncbi.nlm.nih.gov/pubmed/32726297
http://dx.doi.org/10.18632/aging.103558

Ejemplares similares