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Lysine-specific histone demethylase 1B (LSD2/KDM1B) represses p53 expression to promote proliferation and inhibit apoptosis in colorectal cancer through LSD2-mediated H3K4me2 demethylation

Epigenetic alterations have been reported to play critical roles in the development of colorectal cancer (CRC). However, the biological function of the lysine-specific histone demethylase 1B (LSD2/KDM1B) in CRC is not well understood. Therefore, we investigated the characteristics of LSD2 in CRC. We...

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Detalles Bibliográficos
Autores principales:	Cai, Shaoxin, Wang, Jinsi, Zeng, Wei, Cheng, Xuefei, Liu, Lihang, Li, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425427/ https://www.ncbi.nlm.nih.gov/pubmed/32726297 http://dx.doi.org/10.18632/aging.103558

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