ACE2 activator diminazene aceturate ameliorates Alzheimer's disease-like neuropathology and rescues cognitive impairment in SAMP8 mice

Previously, we revealed that brain Ang-(1-7) deficiency was involved in the pathogenesis of sporadic Alzheimer’s disease (AD). We speculated that restoration of brain Ang-(1-7) levels might have a therapeutic effect against AD. However, the relatively short duration of biological effect limited the...

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Detalles Bibliográficos
Autores principales: Duan, Rui, Xue, Xiao, Zhang, Qiao-Quan, Wang, Si-Yu, Gong, Peng-Yu, E, Yan, Jiang, Teng, Zhang, Ying-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425432/
https://www.ncbi.nlm.nih.gov/pubmed/32701063
http://dx.doi.org/10.18632/aging.103544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425432/
https://www.ncbi.nlm.nih.gov/pubmed/32701063
http://dx.doi.org/10.18632/aging.103544

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