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MicroRNA-15a/16/SOX5 axis promotes migration, invasion and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

Fibroblast-like synoviocytes (FLSs) are key effector cells in the pathogenesis of rheumatoid arthritis (RA) and display a unique aggressive tumor-like phenotype with remarkable hyperplasia, increased cell migration and invasion. How FLSs undergo these changes in RA remains unknown. We previously rep...

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Detalles Bibliográficos
Autores principales: Wei, Hua, Wu, Qin, Shi, Yumeng, Luo, Aishu, Lin, Shiyu, Feng, Xiaoke, Jiang, Jintao, Zhang, Miaojia, Wang, Fang, Tan, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425471/
https://www.ncbi.nlm.nih.gov/pubmed/32678069
http://dx.doi.org/10.18632/aging.103480