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Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with anti-atrophic activity on skeletal muscle. Here, we show that not only lifelong overex...

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Detalles Bibliográficos
Autores principales: Agosti, Emanuela, De Feudis, Marilisa, Angelino, Elia, Belli, Roberta, Alves Teixeira, Maraiza, Zaggia, Ivan, Tamiso, Edoardo, Raiteri, Tommaso, Scircoli, Andrea, Ronzoni, Flavio L., Muscaritoli, Maurizio, Graziani, Andrea, Prodam, Flavia, Sampaolesi, Maurilio, Costelli, Paola, Ferraro, Elisabetta, Reano, Simone, Filigheddu, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425472/
https://www.ncbi.nlm.nih.gov/pubmed/32712599
http://dx.doi.org/10.18632/aging.103802