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Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice
Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with anti-atrophic activity on skeletal muscle. Here, we show that not only lifelong overex...
Autores principales: | Agosti, Emanuela, De Feudis, Marilisa, Angelino, Elia, Belli, Roberta, Alves Teixeira, Maraiza, Zaggia, Ivan, Tamiso, Edoardo, Raiteri, Tommaso, Scircoli, Andrea, Ronzoni, Flavio L., Muscaritoli, Maurizio, Graziani, Andrea, Prodam, Flavia, Sampaolesi, Maurilio, Costelli, Paola, Ferraro, Elisabetta, Reano, Simone, Filigheddu, Nicoletta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425472/ https://www.ncbi.nlm.nih.gov/pubmed/32712599 http://dx.doi.org/10.18632/aging.103802 |
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