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Decreased autophagy and fuel switching occur in a senescent hepatic cell model system

Although aging in the liver contributes to the development of chronic liver diseases such as NAFLD and insulin resistance, little is known about the molecular and metabolic details of aging in hepatic cells. To examine these issues, we used sequential oxidative stress with hydrogen peroxide to induc...

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Detalles Bibliográficos
Autores principales: Singh, Brijesh Kumar, Tripathi, Madhulika, Sandireddy, Reddemma, Tikno, Keziah, Zhou, Jin, Yen, Paul Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425478/
https://www.ncbi.nlm.nih.gov/pubmed/32712601
http://dx.doi.org/10.18632/aging.103740