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2-methylbenzoyl berbamine, a multi-targeted inhibitor, suppresses the growth of human osteosarcoma through disabling NF-κB, ERK and AKT signaling networks

Osteosarcoma is the most common malignant bone tumor in children and young adults, and it has a survival rate of only 60% with current cytotoxic chemotherapy combined with aggressive surgery. The aim of this study was to evaluate the therapeutic efficacy of the berbamine derivative 2-methylbenzoyl b...

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Detalles Bibliográficos
Autores principales: Li, Weixu, Li, Yan, Tian, Wenjia, Han, Xiuguo, Zhao, Jie, Xin, Zengfeng, Hu, Hejia, Li, Jun, Hang, Kai, Xu, Rongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425514/
https://www.ncbi.nlm.nih.gov/pubmed/32713851
http://dx.doi.org/10.18632/aging.103565