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Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s disease and frontotemporal lobar degeneration

An early and sizeable loss of basal forebrain cholinergic neurons is a well-characterized feature associated with measurable deficits in spatial learning and cognitive impairment in patients with Alzheimer’s disease. In addition, pro-inflammatory glial cells such as astrocytes and microglia may play...

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Detalles Bibliográficos
Autores principales: Cranston, Anna L, Wysocka, Adrianna, Steczkowska, Marta, Zadrożny, Maciej, Palasz, Ewelina, Harrington, Charles R, Theuring, Franz, Wischik, Claude M, Riedel, Gernot, Niewiadomska, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425524/
https://www.ncbi.nlm.nih.gov/pubmed/32954291
http://dx.doi.org/10.1093/braincomms/fcaa033