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Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy

BACKGROUND: Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes (T2D). Although the cellular and molecular mechanisms of DPN are poorly understood, we and others have shown that altered gene expression and DNA methylation are implicated in disease pathogenesis. Ho...

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Detalles Bibliográficos
Autores principales: Guo, Kai, Eid, Stephanie A., Elzinga, Sarah E., Pacut, Crystal, Feldman, Eva L., Hur, Junguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425575/
https://www.ncbi.nlm.nih.gov/pubmed/32787975
http://dx.doi.org/10.1186/s13148-020-00913-6