Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells

BACKGROUND: The metabolic syndrome (MetS) is a combination of cardiovascular risk-factors, including obesity, hypertension, hyperglycemia, and insulin resistance. MetS may induce senescence in mesenchymal stem/stromal cells (MSC) and impact their micro-RNA (miRNA) content. We hypothesized that MetS...

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Detalles Bibliográficos
Autores principales: Li, Yongxin, Meng, Yu, Zhu, Xiangyang, Saadiq, Ishran M., Jordan, Kyra L., Eirin, Alfonso, Lerman, Lilach O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425605/
https://www.ncbi.nlm.nih.gov/pubmed/32787856
http://dx.doi.org/10.1186/s12964-020-00624-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425605/
https://www.ncbi.nlm.nih.gov/pubmed/32787856
http://dx.doi.org/10.1186/s12964-020-00624-8

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