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Role of Melanin Chemiexcitation in Melanoma Progression and Drug Resistance

Melanoma is the deadliest type of skin cancer. Human melanomas often show hyperactivity of nitric oxide synthase (NOS) and NADPH oxidase (NOX), which, respectively, generate nitric oxide (NO(·)) and superoxide (O(2)(·−)). The NO(·) and O(2) (−) react instantly with each other to generate peroxynitri...

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Detalles Bibliográficos
Autor principal: Premi, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425655/
https://www.ncbi.nlm.nih.gov/pubmed/32850409
http://dx.doi.org/10.3389/fonc.2020.01305