TMEM216 Deletion Causes Mislocalization of Cone Opsin and Rhodopsin and Photoreceptor Degeneration in Zebrafish

PURPOSE: Mutations in TMEM216, a ciliary transition zone tetraspan transmembrane protein, are linked to Joubert syndrome and Meckel syndrome. Photoreceptor degeneration is a prominent phenotype in Joubert syndrome. How TMEM216 contributes to photoreceptor health is poorly understood. METHODS: We hav...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Cao, Shuqin, Yu, Miao, Hu, Huaiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425700/
https://www.ncbi.nlm.nih.gov/pubmed/32687549
http://dx.doi.org/10.1167/iovs.61.8.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425700/
https://www.ncbi.nlm.nih.gov/pubmed/32687549
http://dx.doi.org/10.1167/iovs.61.8.24

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