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Acylcarnitine Abnormalities Implicate Mitochondrial Dysfunction in Patients With Neovascular Age-Related Macular Degeneration

PURPOSE: Abnormalities in lipid metabolism are implicated in age-related macular degeneration (AMD), but the pathways involved remain unclear. We assessed whether acylcarnitine concentrations, a marker of lipid and mitochondrial metabolism, differed between patients with AMD and controls. METHODS: I...

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Detalles Bibliográficos
Autores principales: Liew, Gerald, Tse, Benita, Ho, I-Van, Joachim, Nichole, White, Andrew, Pickford, Russell, Maltby, David, Gopinath, Bamini, Mitchell, Paul, Crossett, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425723/
http://dx.doi.org/10.1167/iovs.61.8.32