ZEB1 Mediates Fibrosis in Corneal Endothelial Mesenchymal Transition Through SP1 and SP3

PURPOSE: ZEB1 is induced during endothelial-mesenchymal transition (EnMT) in the cornea. Induction of SP1 and SP3 by ZEB1 along with identification of putative SP1 and SP3 binding sites in promoters of EnMT-associated gene lead us to investigate their roles in retrocorneal membrane formation in the...

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Detalles Bibliográficos
Autores principales: Lee, JeongGoo, Jung, Eric, Gestoso, Kimberly, Heur, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425726/
https://www.ncbi.nlm.nih.gov/pubmed/32721022
http://dx.doi.org/10.1167/iovs.61.8.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425726/
https://www.ncbi.nlm.nih.gov/pubmed/32721022
http://dx.doi.org/10.1167/iovs.61.8.41

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