Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment

PURPOSE: Gasdermin D (GSDMD) is crucial in neuronal pyroptosis. GSDMD-N and GSDMD-C are two subdomains of the protein GSDMD. GSDMD-N is an executor of pyroptosis, and GSDMD-C has an inhibitory effect on pyroptotic cell death. This study evaluated the role of GSDMD in photoreceptor cell pyroptosis ca...

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Detalles Bibliográficos
Autores principales: Li, Xiaomeng, Liu, Yang, Sun, Mengsha, Gao, Min, Li, Tong, Liang, Jian, Zhai, Yuanqi, Xu, Mengqiao, She, Xiangjun, Yang, Shiqi, Liu, Wenjia, Luo, Xueting, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425730/
https://www.ncbi.nlm.nih.gov/pubmed/32697303
http://dx.doi.org/10.1167/iovs.61.8.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425730/
https://www.ncbi.nlm.nih.gov/pubmed/32697303
http://dx.doi.org/10.1167/iovs.61.8.31

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