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Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes

BACKGROUND: The ongoing COVID-19 pandemic has created an urgency to identify novel vaccine targets for protective immunity against SARS-CoV-2. Early reports identify protective roles for both humoral and cell-mediated immunity for SARS-CoV-2. METHODS: We leveraged our bioinformatics binding predicti...

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Detalles Bibliográficos
Autores principales: Poran, Asaf, Harjanto, Dewi, Malloy, Matthew, Arieta, Christina M., Rothenberg, Daniel A., Lenkala, Divya, van Buuren, Marit M., Addona, Terri A., Rooney, Michael S., Srinivasan, Lakshmi, Gaynor, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425796/
https://www.ncbi.nlm.nih.gov/pubmed/32791978
http://dx.doi.org/10.1186/s13073-020-00767-w